What is Capsaicin?

Capsaicin is the active ingredient in chili peppers that makes them hot. It is used topically for temporary relief of minor aches and pains of muscle and joint associated with arthritis, backache, and strains.

Capsaicin used on the body causes a sensation of heat that activates certain nerve cells. With regular use of capsaicin, this heating effect reduces the amount of substance P, a chemical that acts as a pain messenger in the body.

How does it work?

It drives chemical interactions with sensory neurons by binding to the vanilloid receptor subtype 1 (TRPV1). TRPV1 is a calcium ion channel-type receptor and the function of TRPV1 is detection and regulation of body temperature. Agonists such as capsaicin activate TRPV1 and upon prolonged application, cause TRPV1 activity to decrease (desensitization). This leads to alleviation of pain via the subsequent decrease in the TRPV1 mediated release of inflammatory molecules following exposures to stimuli.

It may take up to 2 weeks of using capsaicin regularly before symptoms improve. For best results, keep using as directed. Pain relief should occur gradually as the substance P in the body is decreased in the nerve cells.

Capsaicin can cause a warming (even burning) sensation wherever it is applied. This sensation is usually mild and should gradually lessen over time with continued regular use of the medicine.

If the burning sensation is painful or causes significant discomfort, wash the treated skin area with soap and cool water. Get medical attention if you have severe burning, pain, swelling, or blistering.

Drug Facts

Active Ingredients- Nonivamide (synthetic capsaicin) 0.036%- Topical Analgesic
Uses: ■ For simple foot pain, arthritis & strains ■ Bruises & Sprains
Warnings For external use only
Do not use ■ On wounds or damaged skin ■ With, or at the same time as, other external analgesic products ■ Allergy Alert: if you are allergic to any ingredients of this product or chili peppers contact a doctor before use ■ If pregnant or breastfeeding consult a healthcare professional before use When using this product ■ You may experience a burning sensation which is normal and related to the way the product works. With regular use, this sensation generally diminishes. ■ Do not use immediately before or after activities such as swimming, showering, sunbathing or intense exercise. ■ Use only as directed ■ Avoid contact with eyes and mucous membranes or rashes
Ask a doctor before use if: Condition worsens, symptoms persist more than 7 days or clear up and occur again within a few days ■ rash, itching or excessive skin irritation develops Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Directions: ■ Clean and dry affected area ■ Remove sock from packaging and place on feet ■ Remove sock after 8 hours of wear ■ Wear sock daily, but not more than 4 times per week
Other Information Avoid storing product in direct sunlight. Protect product from excessive moisture
Inactive Ingredients WS-23 (Cooling agent), Nylon (yarn), Wool (yarn)

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